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FDA Facts About Generics

A generic drug is the same as a brand-name drug in: dosage, safety, strength, quality, the way it works, the way it is taken, the way it should be used US FDA Office

Retin-A

Retin-A
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Tretionin is a natural metabolite of retinol that works by suppressing gene expression, which initiates a modification synthesis of proteins. Retin-A cream penetrates the cells (their membranes) and forms complexes with specific cytoplasmic

Retin-A

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Drug Name

Retin-A

Drug Uses

retionin is a natural metabolite of retinol that works by suppressing gene expression, which initiates a modification synthesis of proteins. Retin-A cream penetrates the cells (their membranes) and forms complexes with specific cytoplasmic receptors that penetrate the cell nucleus and connect with DNA (genetic material). Depending on tissue condition, tretionin inhibits protein synthesis, or activates the process of transcription and increases the number of m-RNA. Retin-A inhibits the gene transcription factor (AP-I), which makes it possible to achieve cessation or reduction of protein synthesis and smoothes the adverse effects of the sun's rays on the skin (including hyperpigmentation).

Drug Class Mechanism

Retin-A reduces the adhesion of those cells that participate in the formation of acne vulgaris, prevents the formation of traffic jams (keratin), and increases the synthesis of substances that are similar to glycosaminoglycans in the corneal epithelium. When applied to open wrinkles Retin-A smoothes skin surface without inflammatory attributes. When Retin A is applied on the closed wrinkles it helps them to become papules or open acne forms. It also prevents the occurrence of new acne. There is evidence that Retin-A inhibits the synthesis of keratin, has antitumor effects and promotes hair growth.

How Taken

Retin A cream is intended for topical use. The drug is applied to the site of the lesion with a thin layer once daily at bedtime and leave on the skin surface for six hours (for dry skin - only 30 minutes). After that you need to wash your face with tap water. If necessary, you can use cream twice daily. The duration of treatment depends on the type of pathology: therapeutic efficacy in the treatment of acne vulgaris is observed in 14-21 days; in most cases it is required in 42-49 days. Optimal clinical results are observed in 90-day therapy. When Retin A is used to remove the adverse effects from the influence of sunlight positive effect is achieved in the period from 4 to 24 weeks. For prophylaxis Retin-A is used once in seven days after having a bath with warm water. The treatment of flat warts begins with small concentrations. In insufficient effect the dose can be gradually increased.

Missed Dose

Try to follow your treatment schedule. If you miss a dose do not use the doubled dose. Apply next evening.

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